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Optimization and upscaling of a fermentation process

  • 2016-2018


  • Optimization and scaling up of a fermentation process for agrobiological product production:
  • Provide advise in the adaptation of the process for the scale up
  • Improve overall performance of the process
  • Reduce operational and fungible costs
  • Selection of the key parameters for monitoring the performance of the process
  • Product chromatographic characterization protocol development to enable the monitoring of the process
  • Fermentation test for production process optimization and upscaling up from flask to 100 liters.
  • Key parameters optimized:
    • Inoculum preparation and adaptation to low cost production media
    • Process conditions: pH control, dO2, agitation, residence time, biomass production, fermentation media
    • Selection of best conditions for increasing the production of the target compounds




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